Email: kosloff@sci.haifa.ac.il

Website: http://koslofflab.haifa.ac.il/

Statement:
The Kosloff lab addresses a fundamental challenge in the field of signal transduction – deciphering how protein structure encodes interaction specificity at the protein family level, thereby “wiring together” signal transduction networks. To achieve our goals, we use complementary computational and experimental approaches. Our research entails the following: 1) Understanding the biophysical and biochemical basis for specificity across large protein families. 2) Using such insights to redesign proteins as tools to modulate and rewire signaling networks. 3) Characterizing specific drug targets at the family level, leading to new therapeutic avenues.

Department: Human Biology | Faculty: Sciences